Not like glass container lines, BFS containers demand a more compact footprint, leading to considerable Room cost savings and higher effectiveness in manufacturing environments that price liberty and flexibility.
It’s normally recommended to investigate and speak to the brands immediately for essentially the most up-to-day info on BFS device availability and specs.
Considering the fact that BFS works by using polymer containers, the respective drug shipping program could be supplied in a variety of fill volumes and container shapes, with minimum changeover time.
Pauzer stated BFS technology has State-of-the-art to The purpose where you can refrigerate or Handle all over the item filling. “At The purpose of dosing, you might be merging by using a warm parison.
During the BFS approach, the plastic raw material is melted, extruded right into a cylindrical tube (referred to as a parison), and fashioned into a container by blowing sterile air or nitrogen into the tube to power the plastic into the shape on the mold.
Evaluating operational efficiencies, BFS packaging systems outshine traditional glass filling traces With regards to Room utilization and output prices.
Use our guidebook for help in choosing the sealing Alternative that best suits your needs and specifications.
Plastic Extrusion: A plastic materials, typically in the shape of a tube or perhaps a strip, is fed into your machine. The plastic material is often a thermoplastic polymer which can be melted and molded.
a hundred% aseptic and with the best attainable versatility in container design. Compact, eco-friendly and with no intricate processes.
Visible inspection poses exclusive difficulties in Blow-Fill-Seal Technology due to the confined transparency of polymer containers as compared to classic glass vials. The partially transparent mother nature in the containers makes it challenging to visually inspect the contents for just about any potential defects or contaminants.
This innovation guarantees the very best standards of sterility and performance which happens to be significant for developing Secure and effective pharmaceuticals. BFS supports the creation of a more info diverse selection of healthcare solutions, such as ophthalmic medicines and parenteral vaccines.
Acknowledged by the FDA as a sophisticated aseptic process to the packaging of sterile pharmaceutical liquids, blow-fill-seal technology is attaining escalating acceptance by furnishing a large assurance of product or service sterility, removing the necessity for human intervention, bettering flexibility in container structure and raising approach uptime.
Temperature considerationsPharmTech: How long will be the merchandise/container at an elevated temperature and so are there any considerations connected with this?
In case the container here is an individual container like a bottle, deep Studying automated inspection is probably going to be a lot more valuable. For any strip of 5 or 10 ampoules over a card joined alongside one another, automated inspection would continue being a challenge.